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目的:对比安列克与欣母沛在预防高危阴道分娩产后出血中的疗效与安全性。方法:选取佛山市南海区第六人民医院2013年1月至2014年12月收治的145例有产后出血高危因素经阴道分娩产妇,随机分为观察组73例和对照组72例,观察组于胎儿娩出后臀部深肌注安列克250μg,对照组于胎儿娩出后臀部深肌注欣母250μg。比较两组产妇产后2 h出血量及产后出血率、不良反应发生率。结果:观察组与对照组产后2 h出血量分别为(224.8±34.3)m L、(212.6±41.0)m L,产后出血率分别为13.7%、11.1%,不良反应发生率分别为31.5%、33.3%,组间比较,差异均无统计学意义(P>0.05)。结论:安列克用于预防高危阴道分娩产后出血安全有效,与欣母沛效果相当,但价格较后者明显降低。
OBJECTIVE: To compare the efficacy and safety of Aileike and Yanmian Pei in the prevention of postpartum hemorrhage in high-risk vaginal delivery. Methods: One hundred and seventy-five pregnant women with vaginal delivery who were at risk of postpartum hemorrhage were selected from Sixth People’s Hospital of Nanhai District, Foshan City from January 2013 to December 2014. They were randomly divided into observation group (73 cases) and control group (72 cases) After the fetus was delivered, the buttocks were injected intramuscularly with 250 μg of intramuscular injection. The control group received 250 μg of intramuscular injection of a deep intramuscular injection of gluteal muscle after the delivery of the fetus. The two groups of postpartum 2 hours postpartum hemorrhage and postpartum hemorrhage rate, the incidence of adverse reactions. Results The amount of bleeding at 2 h after delivery in the observation group and the control group were (224.8 ± 34.3) m L and (212.6 ± 41.0) m L, respectively. The rates of postpartum hemorrhage were 13.7% and 11.1% respectively. The incidence of adverse reactions were 31.5% 33.3%. There was no significant difference between the two groups (P> 0.05). Conclusion: Allilek is safe and effective in preventing postpartum hemorrhage in high-risk vaginal delivery, which is equivalent to that of Yan-Pei. However, the price is significantly lower than that of the latter.