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本研究测定了普通大学生短时间递增负荷力竭运动前后不同时刻血清GH、IGF -I和GHBP的浓度。结果显示 :青年男性短时间递增负荷力竭跑台运动后即刻、运动后 30分钟血清GH浓度明显升高 ,运动后 60分钟呈恢复趋势 ,运动后 60分钟和运动后 2 4小时与运动前相比均无显著性差异 ;运动后即刻血清IGF -I浓度升高 ,但无显著性差异(P >0 0 5) ,运动后 60分钟呈恢复趋势 ,运动后 2 4小时呈下降趋势 ,但亦无显著性差异 ;运动后即刻血清GHBP浓度明显下降 ,运动后30分钟、运动后 60分钟呈恢复趋势 ,运动后 2 4小时未见显著性变化 ;可见 ,成年男性短时间剧烈运动可引起血浆GH浓度短时间急剧升高 ;血浆IGF -I浓度不受短时间剧烈运动的影响 ,且对于内源性GH水平的升高无显著性应答 ;短时间剧烈运动可降低血浆GHBP的水平 ,即减少了组织GHR的数目 ,但在运动后 30～ 60分恢复到安静时水平。推测GH -IGF轴的变化与运动时能源的耗竭和神经递质的变化有关。
The present study measured the concentrations of serum GH, IGF-I and GHBP at different time points before and after the short-term incremental exercise of exhaustive exercise in college students. The results showed that the serum concentration of GH in serum was significantly increased at 30 minutes after exercise in young male rats after short-term increase of load-exhausted treadmill exercise, and recovered at 60 minutes after exercise. At 60 minutes after exercise and 24 hours after exercise, (P> 0.05). After 60 minutes of exercise, the serum IGF-I concentration showed a trend of recovery, but decreased at 24 hours after exercise No significant difference; immediately after exercise serum GHBP concentrations decreased significantly, 30 minutes after exercise, 60 minutes after exercise showed a recovery trend, no significant changes 24 hours after exercise; visible adult male short strenuous exercise can cause plasma GH Concentration in a short period of time increased dramatically; plasma IGF-I concentrations were not affected by strenuous short-term exercise, and no significant response to elevated endogenous GH levels; short-term strenuous exercise reduced plasma GHBP levels, ie decreased The number of GHRs is organized but returned to quiescence 30-60 minutes after exercise. It is speculated that changes in GH-IGF axis are related to energy depletion and neurotransmitter changes during exercise.