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目前认为口服避孕药(OC)可增加心血管疾患的危险性,其机制与凝血因子及/或脂质或脂蛋白改变有关。最近的流行病学研究强调了脂质及脂蛋白在预防动脉硬化中的重要性。当总胆固醇(TC)及甘油三脂(TG)水平很高,高密度脂蛋白-胆固醇(HDL-C)(或 ApoA)值低,低密度脂蛋白-胆固醇(LDL-C)(或 ApoB)值高时,这些疾病的危险性增加。OC 所致的脂质变化已在很多前瞻及回顾性研究中得到证实,但对低剂量的OC 报告不多。此外,这些不同的变化亦随所用雌
Oral contraceptives (OC) are currently considered to increase the risk of cardiovascular disease, the mechanism of which is related to changes in blood coagulation factors and / or lipids or lipoproteins. Recent epidemiological studies have highlighted the importance of lipids and lipoproteins in the prevention of atherosclerosis. When high levels of total cholesterol (TC) and triglyceride (TG), low HDL-C or ApoA, low-density lipoprotein cholesterol (LDL-C) When the value is high, the risk of these diseases increases. Lipid changes caused by OC have been confirmed in many prospective and retrospective studies, but few are reported for low-dose OC. In addition, these different changes are also used with the female