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目的 通过对恶性肿瘤特异性生长因子(Tumor specific crowth factor,TSGF)及血清甲胎蛋白(AFP)的检测,对结果同临床诊断试验进行对比分析,为原发性肝癌的诊断提供依据。方法 选择健康人32例,良性肝病组40例,原发性肝癌患者46例作为研究对象,采用化学比色法测得TSGF浓度,放免法测得AFP浓度。结果 46 例原发性肝癌患者中,单测TSGF敏感度86.96%,单测AFP敏感度69.57%,联合TSGF及AFP敏感度为93.48%。结论 TSGF联合AFP检测可以提高原发性肝癌早期诊断的阳性率。
Objective To compare the results with clinical diagnostic tests by detecting Tumor specific crowth factor (TSGF) and serum alpha-fetoprotein (AFP), so as to provide a basis for the diagnosis of primary liver cancer. Methods 32 healthy subjects, 40 benign liver disease patients and 46 primary hepatocellular carcinoma patients were selected as experimental subjects. The concentration of TSGF was measured by chemical colorimetry and AFP concentration by radioimmunoassay. Results 46 cases of primary liver cancer patients, single TSGA sensitivity 86.96%, single test AFP sensitivity 69.57%, the combined TSGF and AFP sensitivity was 93.48%. Conclusion TSGF combined with AFP test can improve the positive rate of early diagnosis of primary liver cancer.