论文部分内容阅读
PCDH10基因是原钙粘蛋白细胞粘附分子家族的成员之一,是一种重要的抑癌基因。DNA甲基化是抑癌基因失活的机制,PCDH10基因甲基化及其在子宫颈癌癌变中的作用机制还不清楚。现对宫颈癌中PCDH10基因甲基化的相关研究内容进行综述。
PCDH10 gene is a member of the E-cadherin cell adhesion molecule family and is an important tumor suppressor gene. DNA methylation is the mechanism of tumor suppressor gene inactivation. The mechanism of PCDH10 methylation and its role in carcinogenesis of cervical cancer is unclear. Now on the cervical cancer PCDH10 gene methylation related research are reviewed.