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目的观察山茶汤与多索茶碱联合使用在矽肺病治疗当中的作用。方法从该院2013年1月—2015年1月收治的矽肺病患者当中随机选取68例患者作为研究对象,并随机分为二组,其中对照组34例,观察组34例。对照组服用矽肺病治疗药物多索茶碱;观察组在对照组基础上服用山茶汤,每天1剂,连续服用6个疗程,每个疗程30d。在治疗过程中,对对照组以及观察组患者临床体征、肺总有效率、肺部X线变化以及红细胞C3b受体花环率(RBC-C3bRR)进行测定。结果采用山茶汤与多索茶碱联合治疗的观察组总有效率达到88.2%,远高于单独多索茶碱治疗的有效率(67.6%),两者之间差异有统计学意义;且治疗后,观察组患者肺总有效率、肺部X线以及以及红细胞C3b受体花环率相比于对照组而言均有较大程度改善,两者之间差异有统计学意义。结论山茶汤与多索茶碱联合治疗在矽肺病治疗过程中相比于多索茶碱而言效果更佳。
Objective To observe the role of mountain tea soup and doxofylline in the treatment of silicosis. Methods Sixty-eight patients with silicosis admitted to our hospital from January 2013 to January 2015 were randomly divided into two groups: control group (34 cases) and observation group (34 cases). The control group took the silicosis treatment drug Doxofylline. The observation group took the camellia soup on the basis of the control group, taking 1 dose daily for 6 consecutive courses of 30 days each. During the course of treatment, the clinical signs, the total effective rate of lung, the changes of pulmonary X-ray and the RBC-C3bRR of erythrocyte were measured in the control group and the observation group. Results The total effective rate was 88.2% in the observation group treated with both camellia and doxofylline, which was much higher than that in the control group (67.6%). The difference was statistically significant After the observation group patients with total effective lung, pulmonary X ray and erythrocyte C3b receptor rosette rate compared with the control group has a greater degree of improvement, the difference between the two statistically significant. Conclusion Combination of mountain tea and doxofylline is better than that of doxofylline in the treatment of silicosis.