目的:分析不同年龄子宫内膜癌患者的临床病理特点及预后,探讨年轻患者的理想治疗方案。方法:回顾分析1998～2007年诊治的34例(年龄<40岁)子宫内膜癌患者(观察组)和50例(年龄>60岁)的子宫内膜癌患者(对照组)的临床病理资料及预后。结果:观察组患者有高血压、糖尿病仅占53.9%,明显低于对照组(P<0.05),以异常阴道流血为主要症状,有子宫内膜癌家族史者为29.4%高于对照组(P<0.05);早期(Ⅰ期)病例较多占88.2%,高于对照组(P<0.05);组织病理类型以子宫内膜样腺癌为主(94.1%),非子宫内膜样腺癌少见,与对照组差异有统计学意义(P<0.05);组织学分级为高中分化者占94.1%,高于对照组(P<0.05);浸润肌层深度<或局限于内膜内者占72.4%高于对照组(P<0.05);观察组5年生存率93.7%,明显高于对照组(P<0.05)。结论:年轻子宫内膜癌患者以子宫内膜样腺癌为主,临床分期早,预后好,多数患者能够长期生存;治疗应遵循个体化、人性化的原则,保留其生育功能的手术可以尝试。 Objective: To analyze the clinicopathological characteristics and prognosis of patients with endometrial cancer of different ages and to explore the ideal treatment plan for young patients. Methods: The clinical and pathological data of 34 patients with endometrial carcinoma (observation group) and 50 patients (aged> 60 years) with endometrial cancer (control group) diagnosed and treated from 1998 to 2007 were retrospectively analyzed. And prognosis. Results: The observation group had hypertension and diabetes mellitus only accounting for 53.9%, which was significantly lower than that of the control group (P <0.05). Abnormal vaginal bleeding was the main symptom. The family history of endometrial cancer was 29.4% higher than that of the control group P <0.05). The incidence of early stage (Ⅰ stage) was 88.2%, higher than that of the control group (P <0.05). The histopathological types were mainly endometrial adenocarcinoma (94.1%), non-endometrioid adenocarcinoma (P <0.05). The histological grade of high school students was 94.1%, which was higher than that of the control group (P <0.05). The depth of myometrial invasion was