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本文作者研究因胃十二指肠溃疡作胃切除的标本,探讨其肠上皮化生的广泛程度、胃溃疡与十二指肠溃疡的差异以及与胃酸分泌的关系。方法肠上皮化生的诊断乃通过色素内窥镜直接法;观察美蓝吸收着色从机能上来诊断化生部位的广泛性;在溃疡边缘口侧、肛侧、前壁及后壁4点进行活检,从形态学上来诊断化生及其程度;进而在胃十二指肠溃疡切除的新鲜标本,通过杉村、河内等氏的试纸法,分析蔗糖分解酶活性来观察肠上皮化生的广泛程度,并从组织学上进行探讨。结果美蓝着色法和直视下活检的结果,提示胃
The authors studied gastric resection of gastroduodenal ulcer specimens to explore the wide range of intestinal metaplasia, gastric ulcer and duodenal ulcer differences and the relationship between gastric acid secretion. Methods The diagnosis of intestinal metaplasia was determined by the direct method of pigment endoscopy. The absorption of methylene blue was observed to diagnose the extensiveness of the metaplastic region from its function. The biopsy was performed at the ulnar margin, the anus, the anterior wall and the posterior wall , From the morphological diagnosis of metaplasia and its extent; and then in the gastroduodenal ulcer resection of fresh specimens, through the Sugimura, Hanoi et al’s test strip method to analyze the activity of sucrase to observe the wide range of intestinal metaplasia, And from the histological study. Results Methylene blue staining and biopsy results under direct vision, suggesting that the stomach