为了寻找能减轻抗癌药物不良反应的药物,改善化疗效果,动物实验曾发现十全大补汤在不降低顺铂抗癌活性的情况下,可减轻其不良反应,如肾脏毒性、胃肠道毒性及盯脏毒性。此外,还发现当归在十全大补汤的上述活性中起着重要作用。从当归中分离的苹果酸钠具有抑制肾毒性的作用。本次研 In order to find drugs that can reduce the adverse reactions of anticancer drugs and improve the efficacy of chemotherapy, Shiquandabu Decoction has been found to reduce adverse reactions such as renal toxicity, gastrointestinal tract, without reducing the anticancer activity of cisplatin. Toxicity and staring toxicity. In addition, it was also found that Angelica plays an important role in the above activities of Shiquan Dabu Tang. Sodium malate isolated from Angelica sinensis has the effect of inhibiting nephrotoxicity. This research