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有报告铁剂对内脏粘膜有直接腐蚀作用,铁中毒的儿童有呕吐、腹泻和胃肠道出血症状。有关口服铁剂胃肠道的影响,则尚未进行过详细的研究。为此,作者在健康志愿者中研究口服硫酸亚铁对胃肠道症状及内镜所见组织学、大便隐血和粪便失血的影响。材料和方法:无胃肠道出血、胃肠道疾病、胃肠道手术或出血性病史的14例健康志愿者,研究前一周开始禁酒并禁用阿斯匹林、非甾类抗炎药物和维生素C。
Iron has been reported on the visceral mucosa have a direct corrosion, iron poisoning in children with vomiting, diarrhea and gastrointestinal bleeding symptoms. The effects of oral iron on the gastrointestinal tract have not been studied in detail. To this end, the authors studied the effect of oral administration of ferrous sulphate on gastrointestinal symptoms and histology seen in endoscopy, occult occult blood and fecal hemorrhage in healthy volunteers. MATERIALS AND METHODS: A total of 14 healthy volunteers with no history of gastrointestinal bleeding, gastrointestinal disease, gastrointestinal surgery, or hemorrhagic disease began a week before the study banned their use of alcohol and disabled aspirin, non-steroidal anti-inflammatory drugs and vitamins C.