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为探讨一种有效、简便的方法防治药物流产后阴道出血。对106例育龄妇女药物流产后随机双盲口服复方炔诺酮片(每片含炔诺酮0.625mg,炔雌醇0.035mg)或空白片,2片/次,1次/12小时,连服5天。用正铁碱性血红素法定量测定月经出血量;放射免疫法测定用药前后血β-hCG、E_2、P、LH、FSH水平。结果:治疗组阴道出血持续时间及阴道出血量均明显少于对照组,用药后7天血β-hCG、E_2值均较对照组明显下降(P<0.01和P<0.05);对照组用药后LH、P值较治疗组明显下降(P均<0.01)。认为本方法具有简单、价廉及有效的特点,值得进一步研究推广。
To explore an effective and easy way to prevent vaginal bleeding after medical abortion. Randomly double-blind oral norethisterone tablets (each containing norethindrone 0.625mg, ethinyl estradiol 0.035mg) or blank tablets, 2 tablets / time, once / 12 hours, 5 days. The amount of menstrual bleeding was measured by normal ferrous heme. The levels of β-hCG, E_2, P, LH and FSH were measured by radioimmunoassay before and after treatment. Results: The duration of vaginal bleeding and the volume of vaginal bleeding in the treatment group were significantly less than those in the control group. The levels of β-hCG and E 2 in the 7 days after treatment were significantly lower than those in the control group (P <0.01 and P <0.05) LH and P decreased significantly (P <0.01). Considering that this method is simple, cheap and effective, it is worth further studying and popularizing.