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目的对非淋菌性尿道炎(NGU)患者支原体属和衣原体属感染进行分析,并检测其对抗菌药物的敏感性,为合理用药提供依据。方法选择2013年4月-2015年4月在医院检查并确诊为NGU的患者350例,分析患者病原体培养及药敏试验结果,数据采用SPSS19.0软件进行统计分析。结果 350例患者中检出沙眼衣原体(Ct)、解脲脲支原体(Uu)及人支原体(Mh)阳性共168例,总阳性率48.0%;支原体属阳性109例阳性率31.1%,其中Uu阳性91例、Mh阳性8例、Uu与Mh混合阳性10例;衣原体属阳性59例阳性率16.9%;药敏结果显示,Ct对多西环素敏感率最高为96.6%,其次为罗红霉素和交沙霉素,敏感率分别为55.9%和45.8%。结论 NGU感染患者的病原体主要以Uu为主,根据药敏结果建议,首选多西环素、红霉素及交沙霉素进行治疗。
Objective To analyze the infection of Mycoplasma and Chlamydia in patients with non-gonococcal urethritis (NGU) and to test its sensitivity to antibacterial drugs, so as to provide a basis for rational drug use. Methods From April 2013 to April 2015, 350 patients were examined and diagnosed as NGU in the hospital from April 2013 to April 2015. Pathogen culture and drug susceptibility test results were analyzed. The data were analyzed by SPSS19.0 software. Results A total of 168 positive cases of C. trachomatis (Ct), Uu (Ureaplasma urealyticum) and M. hominis (Mh) were detected in 350 cases, with a total positive rate of 48.0%. The positive rate of Mycoplasma in 109 cases was 31.1% 91 cases, Mh positive in 8 cases, Uu and Mh mixed positive in 10 cases; Chlamydia positive in 59 cases positive rate of 16.9%; drug susceptibility results showed that the highest sensitivity of Ct to doxycycline was 96.6%, followed by roxithromycin And josamycin, the sensitivity rates were 55.9% and 45.8% respectively. Conclusion The main pathogens of NGU infection are Uu. According to the results of susceptibility test, the best choice is doxycycline, erythromycin and josamycin.