一、序言 Rous和Murphy等曾将Rous肉瘤组织及上清液接种至鸡胚胚膜及胚内,引起肝,心,胃及胸腔壁长瘤及肝脏出血。以后Keogh报导Rous肉瘤活细胞于接种至鸡胚尿囊绒毛膜(CAM)后引起肝及肺产生大小瘤块;Okar-Blom及Karnofsky等分别将病毒注入胚膜均能引起胚胎肝脏出血;Duran-Reynals指出Rous病毒引起的鸡的出血病变率较成鸡为高,并认为引起出血的原因是血管内皮细胞遭受破坏和在以后出现血 I. Preface Rous and Murphy et al. Inoculated Rous sarcoma tissue and supernatant into chicken embryo embryo and embryo, causing liver, heart, stomach and chest wall tumor and liver hemorrhage. Keogh later reported that Rous sarcoma living cells in the chick embryo chorioallantoic membrane (CAM) caused by the size of the liver and lung tumor mass; Okar-Blom and Karnofsky, respectively, the virus into the embryonic membrane can cause embryo liver hemorrhage; Duran- Reynals pointed out that the Rous virus-induced hemorrhagic lesions in chickens were higher than in adult chickens and that the cause of bleeding was the destruction of vascular endothelial cells and the subsequent appearance of blood