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目的 :对比分析凝血酶联合奥美拉唑联合用药、奥美拉唑单独用药治疗上消化道出血的临床效果。方法 :对本院2014年11月-2015年12月间收治的58例上消化道出血患者的临床资料进行回顾性分析,一组采用凝血酶联合奥美拉唑联合用药,另一组采用奥美拉唑单独用药,然后比较两组患者在平均止血时间、临床疗效、生命体征变化、腹部体征变化及不良反应情况。结果 :凝血酶联合奥美拉唑联合用药组的平均止血时间显著低于奥美拉唑单独用药组,而临床疗效显著优于奥美拉唑单独用药组,两组患者的生命体征变化、腹部体征变化及不良反应等方面没有显著差异。结论 :凝血酶联合奥美拉唑治疗上消化道出血具有非常好的疗效,值得临床推广和应用。
Objective: To compare and analyze the clinical effect of thrombin combined with omeprazole and omeprazole alone in the treatment of upper gastrointestinal bleeding. Methods: The clinical data of 58 patients with upper gastrointestinal bleeding admitted from November 2014 to December 2015 in our hospital were retrospectively analyzed. One group was treated with combination of thrombin and omeprazole, Melaprazole alone, and then compare the two groups of patients in the average hemostasis time, clinical efficacy, changes in vital signs, signs of abdominal changes and adverse reactions. Results: The mean hemostatic time of thrombin combined with omeprazole in combination group was significantly lower than that of omeprazole alone group, while the clinical efficacy was significantly better than that of omeprazole alone group. The changes of vital signs, Signs and adverse reactions such as no significant difference. Conclusion: Thrombin combined with omeprazole in the treatment of upper gastrointestinal bleeding has very good curative effect, which is worthy of clinical promotion and application.