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目的评估小麦纤维素治疗产科卧床保胎患者便秘的疗效及安全性。方法选择卧床保胎并诊断为功能性便秘的100例患者,采用自身对照的方法,给予口服小麦纤维素2周,观察排便困难、粪便性状、排便频率,并进行量化评分,比较治疗前后孕妇排便症状和大便性状。结果小麦纤维素治疗前与治疗后第3、7、14天排便困难评分分别为(2.26±0.38)分、(1.51±0.49)分、(1.22±0.43)分和(0.21±0.37)分;粪便性状评分分别为(2.24±0.39)分、(1.37±0.53)分、(0.65±0.46)分和(0.31±0.41)分。与治疗前症状比较,排便困难显著减轻(P<0.05),粪便性状显著改善(P<0.05)。治疗14d的有效率为82%(82/100)。治疗期间无腹痛、腹泻等不良反应。结论小麦纤维素治疗产科卧床保胎患者便秘安全、疗效确切,值得临床推广应用。
Objective To evaluate the efficacy and safety of wheat cellulose in the treatment of constipation in obstetric and obstetric patients. Methods 100 patients who were hospitalized in bed and diagnosed as functional constipation were given orally administered wheat fiber for 2 weeks by self-control method. The defecation difficulty, stool characteristics and defecation frequency were observed and quantified. The defecation of pregnant women before and after treatment was compared Symptoms and stool characteristics. Results The defecation scores of ((2.26 ± 0.38) points, (1.51 ± 0.49) points, (1.22 ± 0.43) points and (0.21 ± 0.37) points before and 3 and 14 days after treatment of wheat cellulose, The scores of traits were (2.24 ± 0.39) points, (1.37 ± 0.53) points, (0.65 ± 0.46) points and (0.31 ± 0.41) points respectively. Compared with those before treatment, defecation difficulty was significantly reduced (P <0.05) and stool performance was significantly improved (P <0.05). The effective rate of treatment 14d was 82% (82/100). No abdominal pain during treatment, diarrhea and other adverse reactions. Conclusions Wheat cellulose for constipation in obstetric patients with obstetric care in obstetric patients is safe and effective and worthy of clinical application.