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临床治疗癌症患者时为了给予化疗药物、血液制品和胃肠道外营养,常给患者置入中心静脉导管,而血栓形成是置入导管后的常见并发症. 导管相关血栓形成(CRT)可导致肺栓塞、感染以及导管故障. 大部分CRT并无症状,因此需要临床医师对此并发症提高警觉. CRT的诊断依赖于多普勒超声或静脉造影检查,一旦确诊,需权衡抗凝治疗风险与CRT并发症风险后再行决定治疗策略.“,”Central venous catheters are commonly used for the administration of chemotherapy , blood products and parenteral nutrition in patients with haematological malignancy .Thrombosis is a recognized com-plication of the placement of such devices especially in oncology patients.Catheter-related thrombi(CRT) may lead to pulmonary embolism and infection,as well as catheter failure and potential delays in treatment. The vast majority of CRT are asymptomatic,thus a high index of suspicion is required in making the diagno-sis.Doppler ultrasound or venography may be employed to identify CRT.Once confirmed,the initiation of treatment needs to balance between the risk of anticoagulation and potential complications of CRT .