论文部分内容阅读
自1958年Lerner等从牛松果腺提取物中分离并鉴定出褪黑激素(melatonin,MT),对松果腺的研究迅速增多,内容涉及到许多方面,尤其发现它的主要激素MT作用广泛。但由于该领域的研究起步较晚,MT作用的机制还不清楚。近年来随着分子生物学等学科的发展,多学科的相互渗透以及内分泌、神经和免疫系统相互作用,已逐渐形成一个新的研究领域,称为神经内分泌免疫调节(Neu-ro-Endocrine-Immune-Modulation,NEIM)构成机体的整合系统,以下丘脑—垂体—肾上腺轴(HPAA)为该系统的主轴。结合我们初步
Since 1958, Lerner et al. Isolated and identified melatonin (MT) from bovine pineal gland extract. The rapid increase in the study of pineal gland involves many aspects. In particular, it is found that its major hormone MT has a wide range of effects . However, due to the late start of the research in this field, the mechanism of action of MT is still unclear. In recent years, with the development of disciplines such as molecular biology, the interdisciplinary multidisciplinary and the interaction between the endocrine, nervous and immune systems have gradually formed a new research field called the neuroendocrine immune regulation (Neu-ro-Endocrine-Immune -Modulation, NEIM) constitutes the body’s integrated system with the hypothalamic-pituitary-adrenal axis (HPAA) as the main axis of the system. Combined with our preliminary