氨基甙类抗生素对内耳感觉细胞的影响已有很多报道。内耳感觉毛细胞表面包括纤毛表面覆盖着丰富的糖萼,它保持着纤毛的正常形态和稳定性,使纤毛排列成束,并使每根纤毛彼此分开,糖萼的改变与纤毛的融合密切相关。本实验用杂色成年豚鼠10只,另5只作为对照,将0.1ml庆大霉素硫酸盐溶液(含庆大霉素5mg)注入鼓泡,对照组注入等量生理盐 Aminoglycosides on the inner ear sensory cells have been many reports. The inner ear feels that the surface of the hair cells, including the cilia, is covered with a rich glycocalyx which maintains the normal morphology and stability of the cilia, cilia are arranged in bundles and each cilia is separated from the other, and changes in glycocalyx are closely related to cilia fusion . In this experiment, 10 adult guinea pigs with variegated motility were used, and the other 5 rabbits were used as controls to inject 0.1 ml gentamycin sulfate solution (containing gentamicin 5 mg) into the bubbling medium. The control group was infused with the same amount of physiological saline