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孕母患自身免疫性甲状腺疾病,其胎儿因经胎盘获得与孕母疾病相关的免疫球蛋白类型和数量的不同而表现为甲亢或甲减。抗甲状腺药物丙基硫脲嘧啶(PTU)等易通过胎盘抑制胎儿甲状腺素合成。因此需要建立一种子宫内胎儿甲状腺功能低下的检测方法。
Pregnant mother suffering from autoimmune thyroid disease, the fetus through the placenta and maternal disease related to the type and quantity of immunoglobulin showed hyperthyroidism or hypothyroidism. Thyroid drugs propylthiouracil (PTU) and so easily through the placenta inhibition of fetal thyroid hormone synthesis. Therefore, we need to establish a method of detecting intrauterine fetal hypothyroidism.