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目前,基因工程干扰素的效价测定,是采用细胞病变抑制法(CPE)。每毫升干扰素样品能保护半数细胞免受攻击病毒侵害的稀释度,其倒数(ITCD50)即为干扰素的效价(IU/ml)。它的计算用Reed-Muench法,现在我们用概率单位法与之比较,使用的是EL—5100编程计算器。根据等公式
Currently, the titer of the genetically engineered interferon is determined using the cytopathic effect inhibition (CPE) method. Each ml of interferon sample can protect half of cells from the challenge virus, the reciprocal (ITCD50) is the interferon potency (IU / ml). It’s calculated using the Reed-Muench method, and now we compare it with the Probability Unit method, using the EL-5100 Programming Calculator. According to other formulas