我矿72年将克矽平注射液(北京制药厂出产,批号710730—42,每支2ml,每毫升内含克矽平40mg)用于收治的煤矽肺病人的治疗,在临床应用过程中,发生过敏反应二例。例一、李××,男性,39岁,体重47公斤,诊断为Ⅱ期煤矽肺合并肺结核,于72年9月20日第一次接受4%克矽平6ml喷雾,喷后有不适感,以后未再接受喷雾,于72年10月28日首次接受克矽平2ml肌肉注射,注射后不到一分钟,突感上腹烧灼,继之头昏,胸胀厉害,呼吸立感困难。检查见患者面部及全身皮肤潮红,脉搏缓慢但有力,因情况紧急未测血压,即给皮下注射0.1%的盐酸肾上腺素0.5ml,两分钟后皮肤潮红渐消失,自觉症状好转,五分钟后,恢复正常。例二、梁××,男性,47岁,体重57.5公斤,Ⅰ期煤矽肺合并肺结核,第一次肌肉 In the 72 years of my mine, Kesi Ping injection (Beijing Pharmaceutical Factory production, batch number 710730-42, each 2ml, containing 40 grams per square millimeter of silicon) for the treatment of patients with coal silicosis, in the clinical application process, Two cases of allergic reactions occurred. Example 1, Lee × ×, male, 39 years old, weighing 47 kilograms, diagnosed as stage Ⅱ coal silicosis with tuberculosis, on September 20, 72 for the first time received 4% grams of silicon 6ml spray, spray discomfort, After no longer accept the spray, on October 28, 72 for the first time received grams of silicon 2ml intramuscular injection, less than one minute after injection, sudden sensation of abdominal burning, followed by dizziness, chest tightness, breathing difficulties. Check to see patients with facial and systemic skin flushing, slow but powerful pulse, due to emergency blood pressure was not measured, that is, 0.1% subcutaneous injection of epinephrine hydrochloride 0.5ml, two minutes after the skin flushing disappeared, subjective symptoms improved, five minutes later, Back to normal. Example 2, Liang × ×, male, 47 years old, weighing 57.5 kg, stage Ⅰ silicosis of coal with pulmonary tuberculosis, the first muscle