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本文对88例无症状HBsAg携带者随诊四年,并观察其血清学、组织学和免疫组织学的变化。88例中,肝组织正常者63例,轻微改变者15例,共78例。另有慢性注延性肝炎(CPH)6例,慢性活动性肝炎(CAH)4例。88例HBsAg携带者均进行体格检查、肝活组织检查以及血常规、凝血酶原时间、碱性磷酸酶、谷草转氨酶、谷丙转氨酶、蛋白电泳等检查。各种生化检查分别在半年、一年、二年三年、四年后复查。观察期间没有进行治疗。HBsAg和HBcAg在肝细胞内的定位是用直接免疫荣光法进行观察。肝组织正常或轻微改变的78例随诊四年后,复查肝细胞核内来见一例
In this paper, 88 cases of asymptomatic HBsAg carriers were followed up for 4 years, and the changes of serology, histology and immunohistology were observed. In 88 cases, there were 63 cases with normal liver tissues and 15 cases with slight changes, a total of 78 cases. Another chronic chronic hepatitis (CPH) in 6 cases, 4 cases of chronic active hepatitis (CAH). 88 cases of HBsAg carriers were physical examination, liver biopsy and blood, prothrombin time, alkaline phosphatase, aspartate aminotransferase, alanine aminotransferase, protein electrophoresis and other tests. Various biochemical tests were in six months, one year, two years three years, four years after the review. No treatment was performed during the observation period. The localization of HBsAg and HBcAg in hepatocytes was observed by direct immunofluorescence method. 78 cases of liver tissue normal or slight change four years after the follow-up to review a case of liver cell nucleus