损伤时间的确定包括:1)鉴别生前伤和死后伤;2)比较同一个体上的生前损伤,推断生前损伤形成的时间先后次序。生前伤周围,各种炎症因子不断地被激活。相继出现的炎症因子,是确定损伤时间的生物学基础。通过组织学观察证明,白细胞反应是最早出现的炎症征象。损伤后8～12小时,白细胞和激活的成纤维细胞在损伤周围形成一个明显的损伤带。靠近损伤缘的中央区,以组 The determination of injury time includes: 1) identifying prenatal injuries and post-mortem injuries; 2) comparing prenatal injuries on the same individual, and inferring the order in which prenatal injuries are formed. Survival before the injury, a variety of inflammatory factors are constantly being activated. The subsequent emergence of inflammatory cytokines, is to determine the biological basis of injury time. Histological observation showed that leukocyte reaction is the earliest signs of inflammation. Eight to 12 hours after injury, leukocytes and activated fibroblasts formed a distinct lesion around the lesion. Near the injury margin of the central area to group