论文部分内容阅读
目的探讨1997年~2006年山西省围产儿唇腭裂畸形的流行病学特征。方法采用以医院为基础的监测方法收集资料,调查对象为孕28周至产后7天住院分娩的围产儿。结果山西省十年来唇腭裂畸形发生率为22.38/万,其中城镇发生率为18.93/万,农村为27.87/万,城镇与农村分布经χ2检验有显著性差异(P<0.05);男性发生率为25.08/万,女性为19.23/万,男女性别分布经χ2检验有显著性差异(P<0.05);随产妇年龄增加唇腭裂的发生有升高趋势,在≥35岁组发生率最高;十年间仅有53例经产前超声诊断,平均产前诊断率不足10%。结论山西属国内唇腭裂高发区,且十年的年度发生率没有明显变化趋势。产前诊断率偏低,有待进一步提高。
Objective To investigate the epidemiological characteristics of cleft lip and palate deformities in Shanxi Province from 1997 to 2006. Methods A hospital-based monitoring method was used to collect data on pregnant women hospitalized for delivery from 28 weeks pregnant to 7 days postpartum. Results The incidence of cleft lip and palate deformity in Shanxi Province was 22.38 / 10 in 10 years, including 18.93 / 10,000 in urban area and 27.87 / 10 in rural area. The distribution of urban and rural areas was significantly different by χ2 test (P <0.05) (25.08 / females and 19.23 / females respectively). There was a significant difference in gender distribution between men and women (χ2 test, P <0.05). With the increase of maternal age, the incidence of cleft lip and palate had an increasing trend, Only 53 cases of prenatal ultrasound diagnosis, the average prenatal diagnosis rate of less than 10%. Conclusion Shanxi is a high incidence area of domestic cleft lip and palate, and the annual incidence of ten years has no obvious change trend. Prenatal diagnosis rate is low, needs to be further improved.