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目的探讨新生儿急性骨髓炎的临床特点、诊断及早期治疗。方法选择2009—2012年我院NICU收治的急性骨髓炎患儿,回顾性分析其临床特点、诊疗经过及预后情况。结果研究期间共收治8例新生儿急性骨髓炎患儿,发热、肢体活动受限、触摸或被动活动患肢时哭闹明显、患处软组织肿胀等是新生儿急性骨髓炎急性期典型临床表现。5例患儿痊愈,随访10~30个月,均无后遗症发生;穿刺有脓性液体的2例患儿转骨外科行引流、牵引、抗感染等治疗,随访患肢活动存在异常;1例患儿入院不足2天因发生多器官功能衰竭死亡。结论新生儿期急性骨髓炎早期缺乏特异性表现,早期诊断和足疗程治疗可减少后遗症发生。
Objective To investigate the clinical features, diagnosis and early treatment of neonatal acute osteomyelitis. Methods The children with acute osteomyelitis admitted from NICU in our hospital from 2009 to 2012 were retrospectively analyzed for their clinical features, diagnosis, treatment and prognosis. Results A total of 8 infants with acute osteomyelitis were admitted to our hospital during the study period. Fever was found in the children with fever, limb movement was restricted, and crying was obvious when touched or passive limbs. Swelling of the soft tissues in the affected area was a typical clinical manifestation of acute osteomyelitis in neonates. Five children were cured and followed-up for 10-30 months. No sequelae occurred. Two cases of puncture purulent liquid were treated by drainage, traction and anti-infection in osteosurgery. The abnormal limb activity was followed up. One case Children admitted to hospital less than 2 days due to multiple organ failure. Conclusion Early neonatal acute osteomyelitis lack of specific performance early diagnosis and foot treatment can reduce the incidence of sequelae.