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成骨不全症(简称 OI)是由于Ⅰ型胶原结合减少而引起的一种结缔组织疾病。1912年 AdairDight on 首先描述传导性聋为本病的一个病征。
Osteogenesis imperfecta (OI) is a connective tissue disease caused by a decrease in type I collagen binding. 1912 AdairDight on first described the conductive deaf as a symptom of this disease.