血管紧张素转换酶2与血管紧张素转换酶一样参与肾素-血管紧张素系统中血管紧张素的代谢。它通过将血管紧张素Ⅱ水解成血管紧张素1-7对抗血管紧张素转换酶-血管紧张素Ⅱ代谢轴,是平衡肾素-血管紧张素系统内部调节的另一血管紧张素代谢通路。这种系统的内部调节在调节心血管系统活动中起重要作用,其平衡的破坏与高血压等相关疾病的发生发展密切相关,通过调节血管紧张素2来治疗高血压及其并发症可能是本世纪高血压治疗学上的新靶点。 Angiotensin-converting enzyme 2, like angiotensin converting enzyme, is involved in the metabolism of angiotensin in the renin-angiotensin system. By hydrolyzing angiotensin II to angiotensin 1-7, it antagonizes the angiotensin II metabolic axis and is another angiotensin metabolic pathway that mediates the internal regulation of the renin-angiotensin system. The internal regulation of this system plays an important role in the regulation of cardiovascular system activity. The destruction of balance is closely related to the occurrence and development of hypertension-related diseases. The treatment of hypertension and its complications by regulating angiotensin 2 may be New Hypertension Therapy Targets.