狂犬病是世界性流行病。公元100年始知此病与动物有关。此后发现人被狂犬咬伤后,发生恐水现象,因此狂犬病又称为恐水病。1864年始肯定病犬唾液中含有致病因子,能传染给人及家畜。19世纪巴斯德证明,狂犬病毒能侵入到中枢神经系统。1903年内基氏在病兽和人的中枢神经系统组织细胞内发现有病毒小体(即内基氏小体)。现在全世界都加强了对狂犬病的防治。英国、 Rabies is a worldwide epidemic. In 100 AD, we know that the disease is related to animals. Since then found that rabies bites, the phenomenon of fear of water, so rabies, also known as water disease. The beginning of 1864 sick dog saliva contains pathogenic factors, can be transmitted to humans and livestock. The 19th century Pasteur demonstrated that rabies virus can invade the central nervous system. In 1903, Kirschner discovers virion (ie, Neischidemia) in the tissues of the diseased animal and human central nervous system. Now the world has strengthened the prevention and treatment of rabies. United Kingdom,