本文报道用硝硫氰胺甲醇溶液涂肤预防小鼠曼氏血吸虫病的效果。应用4～7周雄性WRAIR小鼠进行试验。硝硫氰胺溶液用甲醇配制,药液浓度为0.1%,(W/V)。于感染曼氏血吸虫尾蚴前工天和3天,将鼠尾在药液中浸泡5分钟或用药液涂搽鼠尾5次,其中部分小鼠在用药后再用水冲洗1/2～3小时。对照组小鼠尾部则用甲醇浸泡或涂搽。实验鼠于感染血吸虫尾蚴后不同时间观察皮肤内的童虫数、皮肤 This article reports the use of nitrocellulose solution of methanol anti-skin effects of Schistosoma mansoni in mice. Male WRAIR mice are used for 4 to 7 weeks. Nitrocyanate solution prepared with methanol, liquid concentration of 0.1% (W / V). Infected with Schistosoma mansoni before the first day and 3 days, the rat tail immersed in the liquid for 5 minutes or 5 minutes with the liquid Tucha rat tail, some of which after treatment in the water and then rinsed 1/2 to 3 hours . The mice in the control group were soaked in or smeared with methanol. Experimental mice were infected with schistosome cercariae sperm at different times after the observation of the number of skin worms, skin