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目的 分析比索洛尔联合辛伐他汀治疗老年不稳定心绞痛的临床效果。方法 从2017年9月至2018年9月到我院进行治疗的不稳定性心绞痛患者中选择78例患者作为研究对象，均按照随机方法分为观察组和对照组，每组平均为39例。两组患者均常规用药辛伐他汀，观察组在对照组用药基础上联合用药比索洛尔。对两组患者经过不同治疗之后的治疗有效率、治疗前后的LVEDD、LVEF指标、心绞痛发作次数和发作时间、用药不良反应发生率、用药前后的疼痛、负面情绪、用药前后的生活质量等进行统计，并对所有数据进行统计学分析和比较。结果 ①观察“,”Objective To analyze the clinical effect of bisoprolol combined with simvastatin in the treatment of senile unstable angina pectoris.Methods Seventy-eight patients with unstable angina pectoris who were treated in our hospital from September 2017 to September 2018 were selected as the research subjects，and they were randomly divided into observation group and control group，with an average of 39 cases in each group.Both groups of patients were routinely treated with simvastatin，and the observation group was treated with bisoprolol on the basis of the control group.After different treatments，the effective rate of treatment，LVEDD and LVEF indexes before and after treatment，the number and time of angina pectoris attacks，the incidence of adverse drug reactions，the pain before and after treatment，negative emotions，and the quality of life before and after treatment were analyzed.，and perform statistical analysis and comparison of all data.Results(1)The total effective rate of the observation group(35 cases，accounting for 89.74%)after the combined treatment of the two drugs was higher than that of the control group(28 cases，accounting for 71.79%)single drug treatment(P＜0.05).(2)Before treatment，there was no significant difference between the observation group and the control group in LVEDD，LVEF index，ECG ST segment，the number of angina pectoris attacks and the time of angina pectoris attack(P＞0.05)，LVEDD，LVEF indexes，ECG ST segment，angina attack times and angina attack time were improved in both groups，but the improvement effect in the observation group was more prominent(P＜0.05).(3)Before treatment，the pain and negative emotions of the patients in the two groups were heavier，and there was no significant difference between them(P＞0.05).After the treatment，the pain and negative emotions of the two groups were improved，however，the improvement in the observation group was more prominent(P＜0.05).(4)The incidence of adverse reactions in the observation group(5 cases，accounting for 12.82%)after the combined treatment was the same as that in the control group(4 cases，accounting for 10.26%)compared with single drug treatment，the difference was no significant(P＞0.05).(5)Before treatment，the quality of life of the two groups of patients was poor and there was no significant difference between them(P＞0.05).The quality of life of the patients was improved，but the improvement of the quality of life of the observation group was more prominent(P＜0.05).Conclusion The combined use of bisoprolol and simvastatin in the treatment of elderly patients with unstable angina pectoris is significantly better than that of simvastatin alone.treatment is always effective.Realizing the adjustment of the patient\'s cardiac function indicators can reduce the frequency and occurrence of angina pectoris，improve the ECG status，regulate the patient\'s negative emotions，reduce pain，and improve the overall quality of life，which is worthy of recommendation.