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目的:研究下肢深静脉血栓形成中西医结合治疗机理。方法:采用中西医结合疗法,并利用体外血栓形成方法,对206例下肢深静脉血栓形成患者进行治疗与检测分析。结果:(1)患者组的体外血栓各值明显地高于健康组(P<0.001);(2)中医辨证分型不同,其体外血栓各值之间存在显著差异(P<0.01~0.001);(3)中西医结合治疗后,体外血栓各值明显改善(P<0.05~0.001)。结论:(1)患者即使在发病后血液仍常处于高凝状态;(2)体外血栓检测结果的变化与本病的病情改变是正相关。(2)体外血栓各值的变化亦可作为中医辨证分型的客观指标。(3)中西医结合治疗后,临床病情改善的同时,体外血栓各值亦明显降低,从而较客观地证实了中西医结合疗法对本病的确切疗效。
Objective: To study the mechanism of TCM-WM combined treatment of deep venous thrombosis of lower extremity. Methods: 206 cases of deep venous thrombosis of lower extremities were treated and tested by the combination of traditional Chinese and western medicine and in vitro thrombosis. Results: (1) The values of extracorporeal thrombosis in patients group were significantly higher than those in healthy group (P <0.001). (2) There were significant differences in the value of extracorporeal thrombus between different TCM syndrome types (P <0. 01 ~ 0.001). (3) The value of extracorporeal thrombosis was significantly improved after the combination of TCM and WM (P <0.05 ~ 0.001). Conclusion: (1) The patient is still hypercoagulable even after the onset of disease; (2) The change of the result of extracorporeal thrombus test is positively correlated with the change of the disease. (2) Changes in the value of extracorporeal thrombus can also be used as an objective indicator of TCM syndrome differentiation. (3) After the combination of TCM and Western medicine treatment, while the clinical condition is improved, the values of extracorporeal thrombosis are also significantly reduced, which objectively confirms the exact effect of TCM-WM combination therapy on this disease.