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目的研究老年原发性高血压 (EH)合并微量白蛋白尿 (MAU)患者的胰岛素及胰岛素敏感性指数的变化。方法 76例老年EH患者按是否合并MAU ,分为MAU组和对照组 ,测定空腹血糖 (FBG)、胰岛素 (FINS)、血脂、胰岛素敏感性指数 (ISI) ,并进行分析。结果MAU组血浆胰岛素显著升高 (P <0 .0 5) ,ISI显著降低 (P <0 .0 5)。结论老年EH患者合并微量白蛋白尿时存在高胰岛素血症和胰岛素抵抗。
Objective To study the changes of insulin and insulin sensitivity index in senile patients with essential hypertension (EH) and microalbuminuria (MAU). Methods 76 elderly EH patients were divided into the MAU group and the control group according to whether they were combined with MAU. The fasting blood glucose (FBG), insulin (FINS), lipids, insulin sensitivity index (ISI) were measured and analyzed. Results Plasma insulin significantly increased in MAU group (P <0.05), and ISI decreased significantly (P <0.05). Conclusions There is hyperinsulinemia and insulin resistance in elderly patients with EH combined with microalbuminuria.