论文部分内容阅读
背景与目的:核磁共振作为乳腺肿瘤新的有效诊断方法已得到广泛肯定,但关于其诊断的敏感性、特异性和精确性报道不一。本研究通过对照病理和免疫组化结果,探讨T2*W首过灌注成像在乳腺肿瘤诊断中的价值。方法:选用乳房肿块患者28例,进行MR检查,根据MRT2*W首次通过灌注成像绘制时间-信号强度曲线图,对病灶最大信号强度下降率和最大信号强度下降时间进行分析,并与手术病理结果相对照。结果:恶性病变组织较良性病变组织有更大的最大信号强度下降率[(44.69±17.07)%vs(17.22±7.49)%,P<0.001]。而良恶性乳腺肿瘤之间的最大信号强度下降时间差异无显著性[(23.94±4.92)s vs(20.02±6.83)s,P>0.05]。结论:T2*W首过灌注成像在乳腺肿瘤诊断中有较高的敏感性和特异性。
BACKGROUND & OBJECTIVE: As a new and effective diagnostic method for breast neoplasms, nuclear magnetic resonance has been widely acknowledged. However, the sensitivity, specificity and accuracy of its diagnosis are reported differently. In this study, we compared the pathological and immunohistochemical results to investigate the value of T2 * W first pass perfusion imaging in the diagnosis of breast tumors. Methods: Twenty-eight patients with breast lumps were selected for MR examination. According to MRT2 * W, the time-signal intensity curve was drawn by perfusion imaging for the first time. The maximum signal intensity decrease rate and the maximum signal intensity decrease time were analyzed and compared with the surgical pathology results Contrast. Results: The rate of maximum signal intensity reduction in malignant lesions was significantly higher than that in benign lesions [(44.69 ± 17.07)% vs (17.22 ± 7.49)%, P <0.001]. However, there was no significant difference in the maximum signal intensity between benign and malignant breast tumors [(23.94 ± 4.92) s vs (20.02 ± 6.83) s, P> 0.05). Conclusion: T2 * W first pass perfusion imaging in the diagnosis of breast cancer have a high sensitivity and specificity.