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目的:探讨多沙唑嗪联合托特罗定在临床上治疗前列腺增生合并膀胱过度活动症疾病的临床治疗效果。方法:对80例前列腺增生合并膀胱过度活动症患者资料进行分析,医护人员根据患者入院时间(单、双日)进行随机分组,分为两组,每组40例。对照组患者采用甲磺酸多沙唑嗪进行治疗,试验组患者采用甲磺酸多沙唑嗪+托特罗定进行综合治疗,两组患者均治疗60 d。医护人员比较两组患者的治疗效果以及患者治疗前、后临床症状评分等指标。结果:试验组患者总有效率为95%,明显高于对照组患者(总有效率75%);两组患者IPSS、QOL、尿急症状评分均有所下降,试验组患者临床治疗效果更好;两组患者治疗后,Qmax、Qave、残余尿量等指标均有所上升,试验组上升幅度更大。结论:临床上,对于这种疾病利用多沙唑嗪联合托特罗定治疗临床效果较好,且这些药物十分安全、可靠,值得推广使用。
Objective: To investigate the clinical effect of doxazosin and tolterodine in the treatment of benign prostatic hyperplasia and overactive bladder diseases. Methods: The data of 80 patients with hyperplasia of bladder accompanied by overactive bladder were analyzed. The medical staff were randomly divided into two groups according to the time of hospital admission (single or double day). Patients in the control group were treated with doxazosin mesylate. Patients in the test group were treated with doxazosin mesylate + tolterodine, and both groups were treated for 60 days. Medical staff compared the treatment effect of two groups of patients and patients before and after treatment, clinical symptoms score and other indicators. Results: The total effective rate was 95% in the experimental group, which was significantly higher than that in the control group (total effective rate was 75%). The scores of IPSS, QOL and urinary urgency were decreased in both groups, and the clinical efficacy of the experimental group was better After treatment, Qmax, Qave, residual urine volume and other indexes increased in both groups, and the test group increased more. Conclusion: Clinically, the treatment of doxazosin and tolterodine for this disease is clinically effective, and these drugs are safe and reliable and should be widely used.