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已知急性 T-淋巴细胞自血病(T-ALL)较急性非T-淋巴细胞白血病预后差,而且前者常发生脑膜浸润。本文收集1980年4月以前6年中的100例 ALL 患者,年龄均在18岁以下。经临床、细胞形态学及组织化学等检查确诊。T-细胞疾病的识别是基于它的母细胞能与羊红细胞形成玫瑰花环。入院后所有患者曾接受标准高电压颅脑照射(18～24Gy)。并在开始治疗的8～10周内接受过至少5个剂量的氨甲喋呤鞘内注射。全身化疗药物包括长春新碱。
Acute T-lymphocytic leukemia (T-ALL) is known to have a poorer prognosis than acute non-T-lymphoblastic leukemia, and meningeal infiltration often occurs in the former. This article collected 100 cases of ALL patients in the 6 years before April 1980, all under the age of 18 years. After clinical, cell morphology and histochemical examination confirmed. The identification of T-cell disease is based on the fact that its mother cell can form a rosette with sheep erythrocytes. All patients admitted to hospital had received standard high voltage cranial irradiation (18-24 Gy). And received at least 5 doses of methotrexate administered intrathecally within 8-10 weeks of starting treatment. Systemic chemotherapy drugs include vincristine.