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目的探讨多巴胺联合硝普钠治疗心肌梗死后左心力衰竭患者的临床疗效。方法选取2014年7月至2016年6月大连市第三人民医院收治的76例心肌梗死后左心力衰竭患者作为研究对象,采用随机综合平衡法将纳入病例分为试验组和对照组,各38例。对照组患者给予常规治疗,试验组患者在对照组基础上采用多巴胺联合硝普钠进行治疗,比较两组患者临床疗效、血压、呼吸频率、心率及不良反应发生情况。结果试验组患者治疗的总有效率明显高于对照组,差异有统计学意义(P<0.05);治疗后两组患者舒张压、收缩压、心率差异均无统计学意义(均P>0.05);而试验组患者呼吸频率水平显著低于对照组,差异有统计学意义(P<0.05);两组患者不良反应发生率比较差异无统计学意义(χ~2=0.629,P=0.428)。结论多巴胺联合硝普钠在心肌梗死后左心力衰竭患者治疗中能够在不增加不良反应的条件下显著改善临床疗效和呼吸功能。
Objective To investigate the clinical efficacy of dopamine combined with sodium nitroprusside in the treatment of patients with left heart failure after myocardial infarction. Methods A total of 76 patients with left heart failure after myocardial infarction admitted to the Third People’s Hospital of Dalian from July 2014 to June 2016 were selected as study subjects. The patients were divided into experimental group and control group by random integrated balance method example. Patients in the control group were given routine treatment. The patients in the test group were treated with dopamine and sodium nitroprusside on the basis of the control group. The clinical efficacy, blood pressure, respiratory rate, heart rate and adverse reactions were compared between the two groups. Results The total effective rate of treatment group was significantly higher than that of control group (P <0.05). There was no significant difference in diastolic blood pressure, systolic blood pressure and heart rate between the two groups after treatment (all P> 0.05) (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (χ ~ 2 = 0.629, P = 0.428). Conclusions Dopamine combined with sodium nitroprusside can significantly improve clinical efficacy and respiratory function in the treatment of patients with left heart failure after myocardial infarction without increasing adverse reactions.