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目的分析脑梗死(CI)患者与正常老年人(NC)的认知性电位P300亚成份构成的特性。方法应用美国仪器和听觉oddball范式,记录了31例CI和40例NC在Fz、Cz、Pz三点上P300,进一步分析P3亚成分。结果NC组在Fz、Cz、Pz点双峰波出现率分别为55%、42.5%和52.5%。CI组在Pz点,P3双峰波出现率低于NC组。CI组潜伏期延迟和波幅低于NC组,有显著性差异。结论P3a和P3b是一个可靠的指标值得进一步研究。
Objective To analyze the characteristics of cognitive potential P300 sub-components in patients with cerebral infarction (CI) and normal controls (NC). Methods Using American odd-odd instrument and auditory oddball paradigm, P300 was recorded in 31 cases of CI and 40 cases of NC at Fz, Cz and Pz. The sub-components of P3 were further analyzed. Results The incidences of bimodal wave at Fz, Cz and Pz were 55%, 42.5% and 52.5% respectively in NC group. CI group at the Pz point, P3 bimodal wave incidence was lower than the NC group. The latency and amplitude of latency in CI group were lower than those in NC group, there was a significant difference. Conclusion P3a and P3b are reliable indicators that warrant further investigation.