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目的分析南京市红十字医院与南京市妇幼保健院药品不良反应(ADR)发生的特点及一般规律,为临床合理用药提供依据。方法采用回顾性研究的方法,对两所医院2012年1月~12月收集上报的56例ADR报告进行统计与分析。结果 56例报告中最易引起ADR的药物为抗菌药物(64.29%);静脉给药发生ADR的病例最多(71.43%);皮肤及其附件结构损害发生率最高(53.57%)。结论医务工作者应全面掌握药物不良反应相关知识,加强用药监测,减少药品不良反应的发生,提高用药安全性。
Objective To analyze the characteristics and general rules of adverse drug reaction (ADR) in Nanjing Red Cross Hospital and Nanjing MCH Hospital and provide the basis for clinical rational drug use. Methods A retrospective study was conducted to analyze and analyze 56 ADR cases collected from January 2012 to December 2012 in two hospitals. Results Most of the 56 reported ADR drugs were antimicrobial drugs (64.29%). The incidence of ADR caused by intravenous injection was the highest (71.43%). The incidence of structural damage of the skin and its accessory organs was the highest (53.57%). Conclusion Medical workers should fully grasp the knowledge of adverse drug reactions, strengthen the monitoring of medication, reduce the incidence of adverse drug reactions and improve the safety of medication.