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为了证实磁共振成像(MRI)中帕金森氏病人(PD)的白质高信号比正常人更为明显,并找出这些异常变化与PD临床特征的可能关系,作者比较了原发性PD病人与正常人MRI异常的出现频率、程度和白质高信号出现的部位,并研究了白质高信号与临床特征如严重程度、病程、治疗的可能关系。 白质高信号(WMHs)分为二类:一类局限于脑室周围(室管膜下)区域,称为脑室周围高信号(PVH),另一类位于白质的深部,称为深部高信号(DH)。
To confirm that white matter hyperintensities of Parkinson’s disease (PD) in magnetic resonance imaging (MRI) are more pronounced than in normal subjects and to identify the possible relationship between these abnormal changes and the clinical features of PD, the authors compared primary PD patients with The frequency and degree of MRI abnormalities in normal subjects and the appearance of white matter hyperintensities were studied. The possible relationship between high white matter signal and clinical features such as severity, course of disease and treatment was also studied. White matter high signal (WMHs) are divided into two categories: one is confined to the periventricular (subependymal) region called the periventricular high signal (PVH) and the other is located deep in the white matter called the deep high signal (DH ).