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帕金森病(PD)的特征性病理改变是黑质多巴胺能神经元大量变性丢失,而当多巴胺神经元丢失达50%以上时才出现相关临床症状,因此探索一种能早期监测PD病理改变的诊断方法,对其进行提前干预非常必要。本文就近年来MRI在PD中的研究进展进行综述。
A characteristic pathological change in Parkinson’s disease (PD) is the loss of substantial denaturation of dopaminergic neurons in the substantia nigra and the associated clinical signs of dopaminergic neurons when they are lost by more than 50%, thus exploring a method for early detection of PD pathological changes Diagnostic methods, its early intervention is necessary. This article reviews the progress of MRI in PD in recent years.