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目的：评价先天性心脏病（先心病）对患儿脑干发育的影响。方法：研究了先心病患儿脑干听觉诱发电位（ＢＡＥＰ）反应，并设正常儿为对照组。结果：年龄＜１２个月，青紫型先心病（ＣＣＨＤ）患儿Ⅰ波潜伏期（ＰＬ）正常，Ｉ－Ｖ波峰间潜伏期（ＩＰＬ）较正常儿显著延长，非青紫型先心病（ＮＣＣＨＤ）患儿Ｉ波ＰＬ、Ｉ－Ｖ波ＩＰＬ均显著延长；４～６岁者，ＮＣＣＨＤ和ＣＣＨＤ无反复缺氧发作者Ｉ波ＰＬ和Ｉ－Ｖ波ＩＰＬ与正常儿无差异，ＣＣＨＤ反复缺氧发作者Ｉ－Ｖ波ＩＰＬ较正常儿显著延长，异常率２３％。结论：先心病可延迟婴儿期脑干发育，缺氧发作可损害脑干功能，对缺氧发作者应尽早进行干预
Objective: To evaluate the impact of congenital heart disease (CHD) on the development of brainstem in children. Methods: The brainstem auditory evoked potentials (BAEP) responses in children with congenital heart disease (CHD) were studied. Normal children were used as control group. Results: The I wave latency (PL) in children with cyanotic heart disease (CCHD) was normal and the I-V wave latency (IPL) was significantly longer than that in the normal children. The children with non-cyanotic congenital heart disease (NCCHD) I wave PL, I-V wave IPL were significantly prolonged; 4 to 6 years of age, NCCHD and CCHD no hypoxia-prone I wave PL and I-V wave IPL and normal children no difference, CCHD repeated hypoxia in the author I -V wave IPL significantly longer than normal children, the abnormal rate of 2.3%. Conclusion: Hypertensive heart disease can delay the development of brainstem in infancy. Hypoxic attack can impair the function of brainstem.