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目的探讨原发性非霍奇金脾淋巴瘤的临床病理特征。方法收集本院2007至2013年期间确诊的5例原发性非霍奇金脾淋巴瘤患者,对其进行临床病理学观察及术后随访。结果原发性非霍奇金脾淋巴瘤的主要临床症状表现为:脾脏肿大、左上腹疼痛、乏力消瘦、贫血、发热等。经B超检测均为脾内多发性占位。5例患者均切除脾脏及术后化疗,其中2例配合放疗,30d后均顺利康复出院。结论原发性非霍奇金脾淋巴瘤的发病率较低,且症状不明显,所以诊断上有一定难度。切除脾既是诊断手段也是治疗手段,术后加以辅助化疗或放疗可以减轻患者痛苦并延长患者的生存时间。
Objective To investigate the clinicopathological features of primary non-Hodgkins lymphoma. Methods Five patients with primary non-Hodgkin’s lymphoma diagnosed in our hospital from 2007 to 2013 were collected and clinically and pathologically observed and followed up. Results The main clinical symptoms of primary non-Hodgkin’s lymphoma were splenomegaly, left upper quadrant pain, fatigue and weight loss, anemia, fever and so on. The B-test are splenic multiple occupancy. All 5 patients underwent resection of the spleen and postoperative chemotherapy, of which 2 patients received radiotherapy and were discharged after 30 days. Conclusion The incidence of primary non-Hodgkin’s lymphoma is low, and the symptoms are not obvious, so it is difficult to diagnose. Excision of the spleen is both a diagnostic tool and a therapeutic tool. Postoperative adjuvant chemotherapy or radiotherapy can reduce the patient’s suffering and extend the patient’s survival time.