论文部分内容阅读
1名26岁女性患者因欲自杀口服0.5mg秋水仙碱70余片,3h后出现恶心、呕吐、腹痛、腹泻等消化道症状。10h后予催吐和洗胃。3d后出现高热39℃,肌肉疼痛,腹痛。实验室检查示:WBC0.7×109/L,PLT7×109/L,ALT94U/L,AST398U/L,ALB25g/L,CK4723U/L,CK-MB169U/L,LDH>1000U/L,α-羟丁酸脱氢酶(α-HBDH)1837U/L,BUN4.09mmol/L,SCr76μmol/L,血钾2.66mmol/L,钙1.6mmol/L,磷0.14mmol/L,血肌红蛋白217μg/L。诊断:急性秋水仙碱中毒。患者出现多脏器系统衰竭。给予非格司亭、输注血小板、纠正电解质紊乱、静脉输液及其他对症治疗。21d后患者除遗有膀胱括约肌麻痹及周围神经感觉异常外,体温、实验室各项指标均恢复正常,出院。
A 26-year-old female patient suicide by oral administration of 0.5mg colchicine more than 70 tablets, 3h after nausea, vomiting, abdominal pain, diarrhea and other gastrointestinal symptoms. After 10h to induce vomiting and gastric lavage. After 3d fever 39 ℃, muscle pain, abdominal pain. Laboratory tests showed: WBC 0.7 × 109 / L, PLT7 × 109 / L, ALT94U / L, AST398U / L, ALB25g / L, CK4723U / L, CK- MB169U / L, LDH> 1000U / 1837U / L of butyrate dehydrogenase (B-HBDH), 4.09mmol / L of BUN, 76μmol / L of SCr, 2.66mmol / L of potassium, 1.6mmol / L of calcium, 0.14mmol / L of phosphorus and 217μg / L of myoglobin . Diagnosis: acute colchicine poisoning. Patients with multiple organ failure. Given filgrastim, platelet transfusion, correct electrolyte disorders, intravenous fluids and other symptomatic treatment. After 21 days, patients with bladder sphincter paralysis and peripheral nerve sensory abnormalities, the body temperature, laboratory indicators returned to normal, discharged.