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目的探讨大黄加甘露醇口服透析治疗慢性肾功能衰竭（ＣＲＦ）的临床效果。方法将６０例ＣＲＦ病人随机分为口服透析组、结肠透析组和口服包醛氧化淀粉组，对临床症状的改善及内生肌酐清除率（Ｃｃｒ）、血清肌酐（ＳＣｒ）、尿素氮（ＢＵＮ）、血脂、血钙等参数在治疗前后的变化进行对比分析。结果口服透析组在临床症状的改善及降低ＳＣｒ、ＢＵＮ，提高Ｃｃｒ调节血脂水平及钙磷代谢诸方面优于结肠透析组，而结肠透析组又优于口服包醛氧化淀粉组。结论大黄加甘露醇口服透析能明显改善ＣＲＦ病人的临床症状，降低血中氮代谢产物，调节血脂水平及钙、磷代谢，延缓病程，对无条件进行血透或腹透的基层医院，不失为一种有效的治疗方法
Objective To investigate the clinical effect of rhubarb plus mannitol oral dialysis on chronic renal failure (CRF). Methods Sixty patients with CRF were randomly divided into oral dialysis group, colon dialysis group and oral dialdehyde-oxidized starch group. The clinical symptoms were improved and the levels of Ccr, SCr, BUN, , Blood lipids, blood calcium and other parameters in the changes before and after the comparative analysis. Results Oral dialysis group was superior to colonic dialysis group in improving clinical symptoms, decreasing SCr, BUN, increasing Ccr regulating blood lipid levels and calcium and phosphorus metabolism, while oral dialysis group was superior to oral dialdehyde aldehyde oxide group. Conclusion Rhubarb and mannitol oral dialysis can significantly improve the clinical symptoms of CRF patients, reduce blood nitrogen metabolites, regulate blood lipid levels and calcium and phosphorus metabolism, delay the course of the unconditional hemodialysis or peritoneal dialysis hospitals, after all, a Effective treatment