采用腺嘌呤诱发大鼠慢性肾衰模型 ,观察了益肾导浊口服液对其防治作用。结果发现本方不仅能改善大鼠肾衰症状 ,而且还能明显改善大鼠的肾脏功能 ,纠正高磷低钙血症。经本方治疗后 ,肾组织内结晶沉积物明显减少 ,部分肾小管形态接近正常 ,对肾小管线粒体具有明显的保护作用 ,可促进肾小管上皮细胞再生 ,表明本方对慢性肾衰大鼠有明显的治疗作用 ,其疗效优于异搏定。 Adenine-induced chronic renal failure model was used to observe the preventive and therapeutic effects of Yishen Guizhuo Oral Liquid. The results found that this party can not only improve the symptoms of renal failure in rats, but also can significantly improve the rat’s kidney function, correct hyperphosphatemia and hypocalcemia. After treatment with this prescription, the crystalline sediments in the renal tissue were significantly reduced, some of the renal tubules were nearly normal in shape, and had obvious protective effects on the renal tubular granules, which promoted the regeneration of renal tubular epithelial cells, indicating that this party has chronic renal failure rats. The obvious therapeutic effect is superior to verapamil.