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目的本项研究是高本底辐射研究组的一项专题，始于１９７２年，旨在探索平均年有效剂量为６４ｍＳｖ的阳江天然放射性高本底辐射照射的致癌危险。１９９１年起中日两国科学家合作继续研究，以累积更多观察人年数，提高统计学精度，并检验以往研究的可重复性。方法合作研究后所获１９８７～１９９５年恶性肿瘤死亡资料是通过回顾性调查或／和前瞻性调查从定群队列中获得。恶性肿瘤死亡现场调查分为队列成员追踪和死因确认两步骤。按外照射年剂量水平，将高本底人群分为高、中、低剂量３个组，以进行内比较。高本底地区３个剂量组与对照组之间的比较采用相对危险（ＲＲ）。ＲＲ和超额相对危险（ＥＲＲ）系数及其９５％置信区间（ＣＩ）计算应用Ｅｐｉｃｕｒｅ中ＡＭＦＩＴ程序。结果１９８７年１月１日定群观察起点人口为１０６５１７人，至１９９５年共累积观察９２６２３８人年，期间共死亡５１６１人，其中恶性肿瘤死亡５５７例。整个高本底地区经性别年龄组调整的全部恶性肿瘤的ＲＲ（９５％ＣＩ）为０９６（０８０，１１５）。就部位别恶性肿瘤而论，白血病、鼻咽癌、食管癌和小肠癌的ＲＲ大于１，而胃癌、肝癌、肺癌、女性乳腺癌、甲状腺癌和淋巴肉瘤的ＲＲ小于１，但差异均无显著性。对全?
Purpose This study, a topic of the High Background Radiation Research Group, began in 1972 with the aim of exploring the carcinogenic risk of exposure to natural radioactive high background radiation from Yangjiang with an average annual effective dose of 6.4 mSv. Since 1991, scientists from China and Japan have continued their cooperation to accumulate more observers, improve statistical accuracy and test the repeatability of previous studies. METHODS Collected data on malignant tumor deaths from 1987 to 1995 were obtained from the cohort by retrospective or / and prospective investigation. Site investigation of death from malignant tumor is divided into follow-up of cohort members and confirmation of cause of death. According to the annual dose level of external radiation, the high background population was divided into three groups of high, medium and low doses for internal comparison. Relative background risk (RR) was used for comparisons between the three dose groups and the control group. RR and Excess Relative Risk (ERR) coefficients and their 95% Confidence Intervals (CIs) were calculated using the AMFIT program in Epicure. Results On January 1, 1987, the population of starting point was 107,517. From 1995 to 1995, a total of 926,238 person-years of observation were observed, with a total of 5161 deaths, of which 557 were malignant tumors. The RR (95% CI) for all malignancies adjusted for gender age groups across the high background was 096 (080,115). The RR of leukemia, nasopharyngeal carcinoma, esophageal cancer and small intestine cancer was more than 1 in the case of partial malignancy. The RR of gastric cancer, liver cancer, lung cancer, female breast cancer, thyroid cancer and lymphosarcoma was less than 1, but the difference was insignificant Sex. Right?