The incremental harmonic balance method was extended to analyze the flutter of systems with multiple structural strong nonlinearities. The strongly nonlinear cubic plunging and pitching stiffness terms were considered in the flutter equations of two-dimensional airfoil. First, the equations were transferred into matrix form, then the vibration process was divided into the persistent incremental processes of vibration moments. And the expression of their solutions could be obtained by using a certain amplitude as control parameter in the harmonic balance process, and then the bifurcation,limit cycle flutter phenomena and the number of harmonic terms were analyzed. Finally,numerical results calculated by the Runge-Kutta method were given to verify the results obtained by the proposed procedure. It has been shown that the incremental harmonic method is effective and precise in the analysis of strongly nonlinear flutter with multiple structural nonlinearities.