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目的研究银背风毛菊Saussurea nivea全草的化学成分。方法应用硅胶色谱技术及重结晶等方法对化合物进行分离,通过现代波谱技术鉴定化合物的结构。结果从银背风毛菊丙酮提取物中分离了11个三萜类化合物,分别鉴定为20(30)-烯-3β-羟基蒲公英烷(1)、20-烯-3β-羟基蒲公英烷(2)、1β-hydroxy-ursa-9(11),12(13)-dien-3β-yl palmitate(3)、1β-hydroxy-oleana-9(11),12-dien-3β-yl palmitate(4)、21α-hydroxy-taraxastero(l5)、20(30)-烯-21α,22α-环氧-3β-蒲公英醇(6)、12-ursene-3β,11α-diol 3-O-palmitate(7)、9(11),12-ursadien-3β-ol 3-O-palmitate(8)、bauereny lacetate(9)、3β-hydroxy-11-oxo-olean-12-enyl palmitate(10)、3β-hydroxy-11α,12α-epoxy-friedoolean-14-enyl palmitate(11)。结论所有化合物均是首次从银背风毛菊中分离得到,其中化合物7～11为首次从风毛菊属植物中分离得到。
Aim To study the chemical constituents of Saussurea nivea. Methods The compounds were isolated by silica gel chromatography and recrystallization. The structures of the compounds were identified by modern spectroscopy. Results Eleven triterpenes were isolated from the acetone extract of Quercus mongolica and identified as 20 (30) -en-3β-hydroxy dandelion (1) and 20-ene-3β- (3), 1β-hydroxy-ursa-9 (11), 12 (13) -dien-3β-yl palmitate 21α-hydroxy-taraxastero (l5) 20 (30) -ene-21α, 22α-epoxy-3β-dandelyl alcohol (6), 12-ursene-3β, (11), 12-ursadien-3β-ol 3-O-palmitate (8), bauereny lacetate (9), 3β-hydroxy-11- oxo-olean- 12-enyl palmitate 12α-epoxy-friedoolean-14-enyl palmitate (11). Conclusion All the compounds were isolated from Prunus densiflora for the first time, of which compounds 7-11 were isolated from the genus Saussurea for the first time.