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目的设计并合成苯骈呋喃类衍生物,并研究其促骨形成作用。方法以苯甲醚为原料,经7步反应得到目标产物,并研究目标产物的促骨形成作用。结果目标化合物的结构经1HNMR、MS确证。结论目标化合物Ⅱa具有较好的促骨形成作用。
OBJECTIVE To design and synthesize benzofuran derivatives and to study their promoting bone formation. Methods Anisole was used as the starting material to obtain the target product after 7 steps and to study the promoting bone formation of the target product. Results The structure of the target compound was confirmed by 1HNMR and MS. Conclusion The target compound Ⅱa has good bone formation promoting effect.