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目的：对市售１１个厂家的曲克芦丁制剂进行质量评价。方法：就含量、溶出度和组分进行分析比较。结果：制剂Ａ为散剂，制剂Ｂ，Ｃ，Ｄ，Ｅ，Ｆ，Ｇ，Ｈ，Ｉ，Ｊ，Ｋ为糖衣片剂，以ＨＰＬＣ测定含量，有６种制剂含羟乙基芦丁在标示量的９０％以上，制剂Ａ，Ｂ，Ｄ，Ｈ，Ｊ，Ｋ中主成分三羟乙基芦丁含量在５０％以上，其中Ａ制剂达８８．２８％。如用ＵＶ法测则不能区分各组分含量。薄层检查证明各制剂均与标示名称相符，只是二羟乙基物、三羟乙基物、四羟乙基物斑点色泽不等，说明含量有差异，有的制剂尚有部分未羟乙基化物。溶出度检查发现，符合中国药典要求的有Ａ，Ｂ，Ｅ，Ｆ，Ｉ，Ｊ和Ｋ等７种。结论：制剂Ａ，Ｂ，Ｈ，Ｊ，Ｋ结果较为满意
OBJECTIVE: To evaluate the quality of troxerutin in 11 commercial manufacturers. Methods: The content, dissolution and composition were analyzed and compared. Results: Formulation A was a powder, and formulations B, C, D, E, F, G, H, I, J and K were sugar-coated tablets. The contents of the preparations were determined by HPLC. , The content of Triethanolamine in the preparations A, B, D, H, J, K was over 50%, and the preparation A reached 88.28%. As with the UV method can not distinguish between the content of each component. Thin-layer examination to prove that the formulations are consistent with the name of the label, but dihydroxyethyl, trihydroxyethyl, tetrahydroxyethyl spots of varying color, indicating that there are differences in content, and some formulations are still some non-hydroxyethyl Chemicals. Dissolution inspection found that in line with the Chinese Pharmacopoeia requirements are A, B, E, F, I, J and K and other 7 species. Conclusion: The results of preparation A, B, H, J, K are satisfactory